138835-25-3Relevant academic research and scientific papers
Bifunctional iron complexes: Efficient catalysts for C=O and C=N reduction in water
Merel, Delphine S.,Elie, Margaux,Lohier, Jean-Francois,Gaillard, Sylvain,Renaud, Jean-Luc
, p. 2939 - 2945 (2013)
The application of bifunctional iron complexes for the hydrogenation of polarized C=X bonds is reported. Two modified Knoelker complexes bearing ionic fragments were synthesized and fully characterized. With these well-defined complexes, the reaction proceeded under mild conditions in pure water, and various alcohols and amines were isolated in good yields. Compared with hydrogenation in organic solvents, better reactivities were observed. Is this the iron age? Well-defined iron-complex-catalyzed reduction of aldehydes, ketones, and imines using molecular hydrogen in water is presented. Under mild conditions, good yields for a broad range of substrates are achieved.
