138876-67-2Relevant academic research and scientific papers
Diastereoface differentiation in addition of lithium enolates to chiral α, β-epoxyaldehydes
Escudier, Jean-Marc,Baltas, Michel,Gorrichon, Liliane
, p. 5253 - 5266 (2007/10/02)
The aldolisation reaction of lithium ester enolates with chiral α,β-epoxyaldehydes 2a-2f has been investigated. The reaction proceeds with diastereofacial preference in favour of the anti isomer (anti: syn ≈ 4:1) and can be greatly enhanced in the case of
ENANTIOSELECTIVE SYNTHESIS OF FOUR ISOMERIC BUILDING BLOCKS USEFUL IN THE SYNTHESIS OF 2-NOR-LEUKOTRIENE ANALOGUES
Bellamy, F. D.,Bondoux, M.,Boubia, B.,Dodey, P.,Mioskowski, C.
, p. 355 - 358 (2007/10/02)
We report, in this letter, the enantioselective synthesis of four isomeric functionalized epoxides (3a, 3b, 3c and 3d) which are useful building blocks for the synthesis of 2-nor-leukotriene analogues.All four epoxides are formally derived from a single n
