138879-88-6

Basic information

• Product Name: D-THREO-CHLORAMPHENICOL, [DICHLOROACETYL-1-14C]
• Synonyms: D-THREO-CHLORAMPHENICOL, [DICHLOROACETYL-1-14C]
• CAS NO: 138879-88-6
• Molecular Formula: C11H12Cl2N2O5
• Molecular Weight: 325.15
• Mol File: 138879-88-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /aqueous ethanol solution
• Storage Temp.: 2-8°C
• CAS DataBase Reference: D-THREO-CHLORAMPHENICOL, [DICHLOROACETYL-1-14C](CAS DataBase Reference)
• NIST Chemistry Reference: D-THREO-CHLORAMPHENICOL, [DICHLOROACETYL-1-14C](138879-88-6)
• EPA Substance Registry System: D-THREO-CHLORAMPHENICOL, [DICHLOROACETYL-1-14C](138879-88-6)

Safety Data

• Hazard Codes: Xi,R
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: UN 2910 7
• Hazardous Substances Data: 138879-88-6(Hazardous Substances Data)

Upstream product

• 119-62-0 (1R,2R)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol 

Relevant articles and documents

Convenient synthesis of D-threo-[dichloroacetyl 1-14C] chloramphenicol

A convenient synthesis of chloramphenicol labelled with carbon-14 in the dichloroacetyl group at the 1 position is described. It was prepared as part of a 4-step sequence from [1-14C] glycine and the product was purified by preparative HPLC. A radiochemical yield of 47% was obtained based on [1- 14C] glycine and the product had a specific activity of 0.47 mCi/mmol. The procedure can be employed for the synthesis of high specific activity [14C] chloramphenicol, labelled at 1, 2 or both the positions of dichloroacetyl group. Copyright