138883-30-4

Upstream product

• 78677-59-5 Ethyl 2-(2-tritylaminothiazol-4-yl)-(Z)-2-(hydroxyimino)acetate 
• 138883-24-6 ethyl 2-(2-aminothiazol-4-yl)-2-p-tosyloxyiminoacetate 
• 76-83-5 trityl chloride 
• 138883-25-7 ethyl 2-(2-tritylaminothiazol-4-yl)-2-p-tosyloxyiminoacetate 
• 100-53-8 phenylmethanethiol 

Relevant academic research and scientific papers

Reaction of aminothiazole-oximetosylates with thiols

The reaction of ethyl 2-(2-aminothiazol-4-yl)-2-tosyloxyiminoacetate and its tritylamino analogue with thiols gave ethyl 2-(5-R-thio-2-amino- or tritylamino-thiazol-4-yl)-2-oxoacetate derivatives. Structures were elucidated by ir, 1H-, 13C-nmr and mass spectroscopy. A reaction mechanism is suggested.