138886-52-9

Upstream product

• 86001-23-2 1,2-bis(2,4,6-trimethylphenyl)ethane-1,2-diol 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 487-68-3 mesytaldehyde 

Downstream Products

• 138886-51-8 4',5'-bis(2,4,6-trimethylphenyl)-4,4a-dihydrospiro<3H,10H-pyrano<4,3-b><1>benzopyran-3,2'-<1,3>dioxolan>-10-one 
• 138886-51-8 4',5'-bis(2,4,6-trimethylphenyl)-4,4a-dihydrospiro<3H,10H-pyrano<4,3-b><1>benzopyran-3,2'-<1,3>dioxolan>-10-one 

Relevant academic research and scientific papers

Nett Asymmetric Conjugate Addition of a Recyclable Acetic Ester Enolate Equivalent

Heterodiene cycloadditions of 3-formyl chromone to ketene acetals derived from C2-symmetric 1,2-diarylethane-1,2-diols are diastereoselective; methanolysis of the cycloadducts derived from (S,S)-hydrobenzoin releases optically enriched methyl 3,4-dihydro-4-oxo-2H-1-benzopyran-2-ylacetate and the optically pure 1,2-diol.

Heterodiene cycloadditoins of C2 symmetric 4,5-disubstituted ketene acetals: the nett asymmetric conjugate addition of recyclable acetic ester enolate equivalents to an activated enone

Heterodiene cycloadditions of 3-formylchromone 2 to a series of ketene acetals 1 derived from C2 symmetric 1,2-diarylethane-1,2-diols are diastereoselective.From (S,S)-1,2-di(o-tolyl)ethane-1,2-diol 6c the major cycloadduct 3c was isolated by crystallization and transformed by acid-catalysed methanolysis into (S)-methyl 4-oxo-3,4-dihydro-2H-1-benzopyran-2-ylacetate 5, together with the original 1,2-diol 6c which could be recycled.The structures of two cyclic carbonates 22a and 22c were determined by X-ray diffraction and used as models in seeking a mechanistic rationale for the stereoselective cycloadditions of the analogous ketene acetals 1a and 1c.