138892-03-2

Upstream product

• 126402-91-3 2,2-Dimethyl-propionic acid (2S,3S,4R,5R)-2-[((S)-1-tert-butylcarbamoyl-2-phenyl-ethyl)-formyl-amino]-4,5-bis-(2,2-dimethyl-propionyloxy)-tetrahydro-pyran-3-yl ester 
• 126402-92-4 2,2-Dimethyl-propionic acid (2S,3S,4R,5R)-2-{[(S)-tert-butylcarbamoyl-(4-chloro-phenyl)-methyl]-formyl-amino}-4,5-bis-(2,2-dimethyl-propionyloxy)-tetrahydro-pyran-3-yl ester 
• 141330-74-7 Diethyl α-<(2,3,4-Tri-O-pivaloyl-D-arabinopyranosyl)amino>benzylphosphonate 
• 126402-94-6 2,2-Dimethyl-propionic acid (2S,3S,4R,5R)-2-[((R)-tert-butylcarbamoyl-thiophen-2-yl-methyl)-formyl-amino]-4,5-bis-(2,2-dimethyl-propionyloxy)-tetrahydro-pyran-3-yl ester 

Relevant academic research and scientific papers

Carbohydrates as chiral templates: Stereoselective synthesis of (R)- and (S)-α-aminophosphonic acid derivatives

The stereoselective synthesis of diethyl (S)- or (R)-α-[(O-pivaloyl-hexapyranosyl)amino]benzylphosphonates is achieved via Lewis acid catalyzed addition of diethyl phosphite to O-pivaloylated N-benzylidene-β-D-galactosylamine or N-benzylidene-α-D-arabinop

Stereoselective synthesis of L-amino acids via Strecker and Ugi reactions on carbohydrate templates

L-Amino acid derivatives are stereoselectively synthesized in high yield using 2,3,4-tri-O-pivaloyl-α-D-arabinopyranosylamine or 2,3,4-tri-O-pivaloyl-β-L-fucopyranosylamine as the chiral auxiliary in Strecker and Ugi reactions.

CARBOHYDRATES AS CHIRAL TEMPLATES: DIASTEREOSELECTIVE UGI SYNTHESIS OF (S)-AMINO ACIDS USING O-ACYLATED D-ARABINOPYRANOSYLAMINE AS THE AUXILIARY

Enantiomerically pure (S)-amino acids are synthesized via a highly diastereoselective Ugi reaction using 2,3,4-tri-O-pivaloyl-α-D-arabinopyranosylamine as the chiral template.