2,4(1H,3H)-Pyrimidinedione, 6-amino-3-(2-propynyl)-, also known as 6-amino-3-propargyluracil, is a chemical compound with the molecular formula C7H6N2O2. It is a yellow crystalline solid that serves as a versatile building block in the synthesis of various pharmaceuticals and agrochemicals. 2,4(1H,3H)-Pyrimidinedione, 6-amino-3-(2-propynyl)is recognized for its ability to inhibit the enzyme dihydroorotate dehydrogenase, which is crucial in the biosynthesis of pyrimidines. Its unique properties make it a promising candidate for the development of treatments for cancer, autoimmune diseases, and antiviral drugs.
138895-22-4
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Basic information
- Product Name: 2,4(1H,3H)-Pyrimidinedione, 6-amino-3-(2-propynyl)-
- Synonyms:
- CAS NO:138895-22-4
- Molecular Formula: C7H7N3O2
- Molecular Weight: 165.151
- EINECS: N/A
- Product Categories: N/A
- Mol File: 138895-22-4.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: N/A
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 2,4(1H,3H)-Pyrimidinedione, 6-amino-3-(2-propynyl)-(CAS DataBase Reference)
- NIST Chemistry Reference: 2,4(1H,3H)-Pyrimidinedione, 6-amino-3-(2-propynyl)-(138895-22-4)
- EPA Substance Registry System: 2,4(1H,3H)-Pyrimidinedione, 6-amino-3-(2-propynyl)-(138895-22-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 138895-22-4(Hazardous Substances Data)
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138895-22-4 Usage
Uses
Used in Pharmaceutical Industry:2,4(1H,3H)-Pyrimidinedione, 6-amino-3-(2-propynyl)is used as an intermediate in the synthesis of pharmaceuticals for its ability to inhibit the enzyme dihydroorotate dehydrogenase. This inhibition is particularly relevant in the development of treatments for cancer and autoimmune diseases, as it can disrupt the biosynthesis of pyrimidines, which are essential for the replication of certain pathogens and the proliferation of cancer cells.
Used in Antiviral Drug Development:
In the field of antiviral research, 2,4(1H,3H)-Pyrimidinedione, 6-amino-3-(2-propynyl)is utilized as a key compound for the development of new antiviral drugs. Its demonstrated effectiveness in inhibiting certain viruses makes it a valuable asset in creating medications that can combat viral infections by targeting the biosynthetic pathways of the virus.
Used in Agrochemical Industry:
2,4(1H,3H)-Pyrimidinedione, 6-amino-3-(2-propynyl)also finds applications in the agrochemical industry, where it is used as a building block for the synthesis of various agrochemicals. Its ability to inhibit essential biosynthetic pathways can be harnessed to create compounds that control or eliminate pests and diseases in agriculture, thereby contributing to increased crop yields and food security.
Check Digit Verification of cas no
The CAS Registry Mumber 138895-22-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,8,8,9 and 5 respectively; the second part has 2 digits, 2 and 2 respectively.Calculate Digit Verification of CAS Registry Number 138895-22:
(8*1)+(7*3)+(6*8)+(5*8)+(4*9)+(3*5)+(2*2)+(1*2)=174
174 % 10 = 4
So 138895-22-4 is a valid CAS Registry Number.
138895-22-4Upstream product
138895-22-4Downstream Products
- 174519-11-0 3-Benzyl-8-[(E)-2-(3-chloro-phenyl)-vinyl]-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione
- 174519-05-2 (E)-N-(6-Amino-1-benzyl-2,4-dioxo-3-prop-2-ynyl-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(3-chloro-phenyl)-acrylamide
- 174519-10-9 8-[(E)-2-(3-Chloro-phenyl)-vinyl]-3-isobutyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione
- 174519-09-6 8-[(E)-2-(3-Chloro-phenyl)-vinyl]-3-propyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione
- 174519-04-1 (E)-N-(6-Amino-2,4-dioxo-1-propyl-3-prop-2-ynyl-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(3-chloro-phenyl)-acrylamide
- 174519-02-9 (E)-N-(6-Amino-1-methyl-2,4-dioxo-3-prop-2-ynyl-1,2,3,4-tetrahydro-pyrimidin-5-yl)-3-(3-chloro-phenyl)-acrylamide
- 174519-08-5 8-[(E)-2-(3-Chloro-phenyl)-vinyl]-3-methyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione
- 174518-99-1 6-amino-5-(3-chlorocinnamoylamino)-3-(prop-2-ynyl)uracil
- 174519-07-4 3-Benzyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione
- 174519-01-8 N-(6-Amino-1-benzyl-2,4-dioxo-3-prop-2-ynyl-1,2,3,4-tetrahydro-pyrimidin-5-yl)-formamide
- 702697-10-7 3-{6-amino-5-[3-(3-methoxyphenyl)acryloylamino]-2,4-dioxo-3-prop-2-ynyl-3,4-dihydro-2H-pyrimidin-1-yl}propyl acetate
- 702697-20-9 (E)-8-[2-(3-methoxyphenyl)vinyl]-1-prop-2-ynyl-3-(3-trimethylsilanyloxypropyl)-3,7-dihydropurine-2,6-dione
- 702697-16-3 (E)-3-[8-[2-(3-methoxyphenyl)vinyl]-7-methyl-2,6-dioxo-1-prop-2-ynyl-1,2,6,7-tetrahydropurin-3-yl]propyl acetate
- 702697-13-0 (E)-3-[8-[2-(3-methoxyphenyl)vinyl]-2,6-dioxo-1-prop-2-ynyl-1,2,6,7-tetrahydropurin-3-yl]propyl acetate
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2,4(1H,3H)-Pyrimidinedione, 6-amino-3-(2-propynyl)-
