138913-26-5

Basic information

• Product Name: 1H-1,3-Diazepine,hexahydro-1,3-dimethyl-(9CI)
• Synonyms: 1H-1,3-Diazepine,hexahydro-1,3-dimethyl-(9CI)
• CAS NO: 138913-26-5
• Molecular Formula: C7H16N2
• Molecular Weight: 128.21534
• Product Categories: AMINETERTIARY
• Mol File: 138913-26-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-1,3-Diazepine,hexahydro-1,3-dimethyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,3-Diazepine,hexahydro-1,3-dimethyl-(9CI)(138913-26-5)
• EPA Substance Registry System: 1H-1,3-Diazepine,hexahydro-1,3-dimethyl-(9CI)(138913-26-5)

Safety Data

• Hazardous Substances Data: 138913-26-5(Hazardous Substances Data)

Upstream product

• 50-00-0 formaldehyd 
• 16011-97-5 N,N'-dimethyl-1,4-butanediamine 
• 67-56-1 methanol 
• 102600-39-5 N,N'-dimethyl-N,N'-butanediyl-bis-toluene-4-sulfonamide 

Relevant articles and documents

Using Methanol as a Formaldehyde Surrogate for Sustainable Synthesis of N-Heterocycles via Manganese-Catalyzed Dehydrogenative Cyclization

The development of an efficient and sustainable synthetic route for formaldehyde production from renewable feedstock, especially in combination with a subsequent transformation to straightforwardly construct valuable chemicals, is highly desirable. Herein, we report a novel manganese-catalyzed dehydrogenative cyclization of methanol as a formaldehyde surrogate with a variety of dinucleophiles for facile synthesis of N-heterocycles. The in situ generated formaldehyde via catalytic methanol dehydrogenation can be selectively trapped by diverse dinucleophiles to avoid several possible side reactions. The utility of this transformation is further highlighted by its successful application to the synthesis of 13C-labeled N-heterocycles using 13CH3OH as a readily accessible 13C-isotope reagent.