138914-80-4

Basic information

• Product Name: 2-chloro-(4-carboxyphenoxy)phenylacetic acid
• Synonyms: 2-chloro-(4-carboxyphenoxy)phenylacetic acid
• CAS NO: 138914-80-4
• Molecular Weight: 306.702
• Mol File: 138914-80-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-(4-carboxyphenoxy)phenylacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-(4-carboxyphenoxy)phenylacetic acid(138914-80-4)
• EPA Substance Registry System: 2-chloro-(4-carboxyphenoxy)phenylacetic acid(138914-80-4)

Safety Data

• Hazardous Substances Data: 138914-80-4(Hazardous Substances Data)

Upstream product

• 54551-83-6 methyl 2-(2,6-dichlorophenyl)acetate 
• 6575-24-2 2-(2,6-dichlorophenyl)acetic acid 
• 138914-79-1 methyl 2-chloro-6-(4-methoxycarbonylphenoxy)phenylacetate 

Relevant articles and documents

The Synthesis of 1,8-Disubstituted 10,11-Dihydrodibenzoxepin-10-ones. Analogues of Anaesthetic Steroids

1,8-Disubstituted 10,11-dihydrodibenzoxepin-10-ones 4a, b and 5a, b have been synthesized as analogues of steroid anaesthetics 2 and 3 respectively.The novel partial Ullmann reaction between methyl 2,6-dichlorophenylacetate 7 and 4-substituted phenols 8a, b gave diphenyl ether derivatives 9a, b.The latter were then hydrolysed and cyclodehydrated to give 1,8-disubstituted 10,11-dihydrodibenzoxepin-10-ones 11a, b which underwent selective funtional group transformations to give 4a, 5a and 4b, 5b respectively.Lithium borohydride reduction of the ester 13b to the benzyl alcohol 14b proceeded without reduction of the enol ether function.