138914-96-2

Basic information

• Product Name: C₁₈H₁₆FN₃OS
• Synonyms: C₁₈H₁₆FN₃OS
• CAS NO: 138914-96-2
• Molecular Weight: 341.409
• Mol File: 138914-96-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₆FN₃OS(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₆FN₃OS(138914-96-2)
• EPA Substance Registry System: C₁₈H₁₆FN₃OS(138914-96-2)

Safety Data

• Hazardous Substances Data: 138914-96-2(Hazardous Substances Data)

Upstream product

• 132252-86-9 (Z)-2-Cyano-3-(4-fluoro-phenyl)-thioacrylamide 
• 17282-41-6 N-acetonylpyridinium bromide 
• 125240-16-6 2,6-diamino-4-(4-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile 

Downstream Products

• 94639-17-5 4-(4-Fluoro-phenyl)-6-methyl-2-thioxo-1,2-dihydro-pyridine-3-carbonitrile 

Relevant articles and documents

CYCLIZATION OF NITRILES. XLIX. DEGENERATED STEREOSELECTIVE CROSS-RECYCLIZATION OF ENAMINONITRILES OF THE 1,3-DITHIACYCLOHEXENE AND 4H-THIOPYRAN SERIES WITH PYRIDINIUM YLIDES INTO SUBSTITUTED 3-(PYRIDINIO)-5-CYANO-3,4-TRANS-1,2,3,4-TETRAHYDRO-6-PYRIDINE-THIOLATES

The reactions of enaminonitriles of 1,3-dithiacyclohexenes and 4H-thiopyrans with pyridinium ylides proceed highly regio- and stereoselectively according to the cross-recyclization mode with the formation of substituted 3-(1-pyridino)-5-cyano-3,4-trans-1,2,3,4-tetrahydro-6-pyridinethiolates.These reactions have a common intermediate, arylmethylenecyanothioacetamide, which was used in the synthesis of substituted 6-pyridinethiolates.Because of the common nature of the structure of the initial enaminonitriles of 1,3-dithiacyclohexenes and 4H-thiopyrans, the intermediate compounds and the reaction end products, the above recyclization reactions were designated as degenerated reactions.