138924-43-3Relevant articles and documents
Mechanistic Insight into the Dehydro-Diels-Alder Reaction of Styrene-Ynes
Kocsis, Laura S.,Kagalwala, Husain N.,Mutto, Sharlene,Godugu, Bhaskar,Bernhard, Stefan,Tantillo, Dean J.,Brummond, Kay M.
, p. 11686 - 11698 (2015)
The Diels-Alder reaction represents one of the most thoroughly studied and well-understood synthetic transformations for the assembly of six-membered rings. Although intramolecular dehydro-Diels-Alder (IMDDA) reactions have previously been employed for th
Hydroamination versus Allylic Amination in Iridium-Catalyzed Reactions of Allylic Acetates with Amines: 1,3-Aminoalcohols via Ester-Directed Regioselectivity
Kim, Seung Wook,Wurm, Thomas,Brito, Gilmar A.,Jung, Woo-Ok,Zbieg, Jason R.,Stivala, Craig E.,Krische, Michael J.
supporting information, p. 9087 - 9090 (2018/08/03)
In the presence of a neutral dppf-modified iridium catalyst and Cs2CO3, linear allylic acetates react with primary amines to form products of hydroamination with complete 1,3-regioselectivity. The collective data, including deuterium labeling studies, corroborate a catalytic mechanism involving rapid, reversible acetate-directed aminoiridation with inner-sphere/outer-sphere crossover followed by turnover-limiting proto-demetalation mediated by amine.
Asymmetric catalysis. Mechanism of asymmetric catalytic intramolecular hydrosilation
Bergens, Steven H.,Noheda, Pedro,Whelan, John,Bosnich
, p. 2128 - 2135 (2007/10/02)
The mechanism of asymmetric catalytic intramolecular hydrosilation using [Rh(diphosphine)]+ catalysts has been investigated by the use of specifically labeled deuterated substrates. It is concluded that oxidative addition of the silicon hydride