1389439-77-3Relevant academic research and scientific papers
Preparation method of azabenzoazulene derivative
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, (2021/06/13)
The invention belongs to the technical field of preparation of medicinal chemistry, and particularly relates to a preparation method of an azabenzoazulene derivative, ethyl acetoacetate and triethyl orthoformate are used as raw materials, and the azabenzoazulene derivative is prepared after a series of reactions. Compared with the existing synthetic method of the azabenzoazulene derivative, the method disclosed by the invention has the advantages that the raw materials are simple and easy to obtain, the synthetic route is simple and easy to implement, the yield is high, the operation is convenient, the cost is low, and the method can be easily applied to laboratory drug modification.
ANTITUMOR AZA-BENZO [F] AZULEN DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF
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, (2015/02/18)
The present invention relates to the field of pharmaceutical chemistry, and particularly to an aza-benzo[f]azulen derivative (I) and an antitumor effect thereof Pharmacological tests show that the compound of the present invention has in vitro and in vivo antitumor activities, and can be developed into clinical drugs for treating or controlling diseases such as stomach cancer, lung cancer, liver cancer, breast cancer, colon cancer, prostate cancer, and oral cancer.
ANTITUMOR AZA-BENZO[F]AZULEN DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF
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, (2015/01/18)
The present invention relates to the field of pharmaceutical chemistry, and particularly to an aza-benzo[f]azulen derivative (I) and an antitumor effect thereof. Pharmacological tests show that the compound of the present invention has in vitro and in vivo antitumor activities, and can be developed into clinical drugs for treating or controlling diseases such as stomach cancer, lung cancer, liver cancer, breast cancer, colon cancer, prostate cancer, and oral cancer.
