139004-93-6

Basic information

• Product Name: (R)-PIPERIDIN-2-YLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: (S)-tert-butyl piperidin-2-ylmethylcarbamate hydrochloride;S-2-BOC-AMINOMETHYL-PIPERIDINE-HCl;(S)-tert-Butyl (piperidin-2-ylMethyl)carbaMate;CarbaMic acid, N-[(2S)-2-piperidinylMethyl]-, 1,1-diMethylethyl ester;(S)-2-[[(tert-Butoxycarbonyl)amino]methyl]piperidine;tert-Butyl ((2S)-piperidin-2-ylmethyl)carbamate;tert-butyl N-[(2S)-piperidin-2-ylmethyl]carbamate;tert-butyl (S)-(piperidin-2-ylmethyl)carbamate
• CAS NO: 139004-93-6
• Molecular Formula: C₁₁H₂₂N₂O₂
• Molecular Weight: 214.31
• Mol File: 139004-93-6.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 287.9°C at 760 mmHg
• Flash Point: 127.9°C
• Appearance: /
• Density: 1.01g/cm³
• Vapor Pressure: 0.00242mmHg at 25°C
• Refractive Index: 1.485
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (R)-PIPERIDIN-2-YLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-PIPERIDIN-2-YLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER(139004-93-6)
• EPA Substance Registry System: (R)-PIPERIDIN-2-YLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER(139004-93-6)

Safety Data

• Hazardous Substances Data: 139004-93-6(Hazardous Substances Data)

Usage

Uses

Chiral building block developed using Liverpool ChiroChem-patented technology.

InChI:InChI=1/C11H22N2O2/c1-11(2,3)15-10(14)13(4)9-7-5-6-8-12-9/h9,12H,5-8H2,1-4H3

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 153918-98-0 (2R)-2-<(2S)-2-(aminomethyl)piperidin-1-yl>-2-phenylethanol 
• 248914-23-0 tert-butyl ({(2S)-1-[(1R)-2-hydroxy-1-phenylethyl]piperidin-2-yl}methyl)carbamate 
• 3105-95-1 pipecolinic acid 
• 139004-91-4 (S)-1-Benzyl-piperidine-2-carboxylic acid amide 
• 139004-92-5 (S)-N-benzyl-2-aminomethylpiperidine 
• 19889-77-1 (2S)-2-piperidinecarboxamide 
• 18650-39-0 (S)-methyl pipecolinate hydrochloride 

Downstream Products

• 248914-24-1 tert-butyl {[(2S)-1-(chloroacetyl)piperidin-2-yl]methyl}carbamate 
• 380899-36-5 tert-butyl [((2S)-1-{[5-(4-fluorophenyl)-2-methyl-1,3-thiazol-4-yl]carbonyl}piperidin-2-yl)methyl]carbamate 
• 1083283-00-4 (S)-(2-aminomethyl-piperidin-1-yl)-[2-cyclopropyl-5-(2-fluoro-phenyl)-thiazol-4-yl]-methanone hydrochloride 
• 1083281-00-8 (S)-N-{1-[2-cyclopropyl-5-(2-fluoro-phenyl)-thiazole-4-carbonyl]-piperidin-2-ylmethyl}-3-methyl-benzamide 
• 380899-51-4 C₁₇H₂₀FN₃OS 
• 879609-50-4 (S)-N-((1-isobutylpiperidin-2-yl)methyl)-2-methylpropan-1-amine 
• 1137129-14-6 (S)-{1-[2-bromo-5-(4-fluoro-phenyl)-thiazole-4-carbonyl]-piperidin-2-ylmethyl}-carbamic acid tert-butyl ester 
• 1083282-96-5 (S)-{1-[2-cyclopropyl-5-(2-fluoro-phenyl)-thiazole-4-carbonyl]-piperidin-2-ylmethyl}-carbamic acid tert-butyl ester 
• 248914-28-5 (S)-4-oxooctahydro-2H-pyrido[1,2-a]pyrazine 
• 179605-63-1 (S)-octahydro-2H-pyrido[1,2-a]pyrazine 

Relevant articles and documents

POLYMORPH FORMS OF (S)-2-((4-BENZOFURANYL)CARBONYLAMINOMETHYL)-1-((4-(2-METHYL-5-(4-FLUOROPHENYL)THIAZOLYL)CARBONYL)PIPERIDINE

New crystalline forms of (S)-2-((4-benzofuranyl)carbonylamino methyl)-1-((4-(2-methyl-5-(4-fluorophenyl))thiazolyl)carbonyl)piperidine, methods for their preparation and use in medicine as orexin receptor antagonist.

Asymmetric synthesis of octahydro-2H-pyrido[1,2-a]-pyrazines

A series of optically pure octahydro-2H-pyrido[1,2-a]pyrazines has been prepared from (-)-2-cyano-6-phenyloxazolopiperidine (4). 2H-Pyrido[1,2- a]pyrazin-3-(4H)-one (7) and octahydro-2H-pyrido[1,2-a]pyrazine (14) were obtained from diamino alcohol (5) by