139023-07-7Relevant academic research and scientific papers
γ-BROMOACETOACETANILIDES IN HETEROCYCLIC SYNTHESIS: A CONVENIENT SYNTHESIS OF POLYFUNCTIONALLY SUBSTITUTED 2,3-DIHYDROTHIAZOLE, PYRIDIN-2-ONE, 1,2,3-TRIAZINE, OXAZOLOPYRIDINE AND PYRAZOLOPYRIDINE DERIVATIVES
Mohareb, Rafat M.,Abdel-Sayed, Nadia I.,Sherif, Sherif M.
, p. 119 - 130 (2007/10/02)
The active methylene reagents 1a-d reacted with phenyl isothiocyanate in basic DMF at room temperature to yield the non-isolable 1:1 adducts 2a-d.In situ cyclization of the latter with γ-bromoacetoanilides afforded the 2,3-dihydrothiazoles 3a-h.The reacti
