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(E)-3-(4-amino-2-fluorophenyl)acrylic Acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1390641-83-4

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1390641-83-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1390641-83-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,0,6,4 and 1 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1390641-83:
(9*1)+(8*3)+(7*9)+(6*0)+(5*6)+(4*4)+(3*1)+(2*8)+(1*3)=164
164 % 10 = 4
So 1390641-83-4 is a valid CAS Registry Number.

1390641-83-4Relevant academic research and scientific papers

Free fatty acid receptor 1 (FFA1/GPR40) agonists: Mesylpropoxy appendage lowers lipophilicity and improves ADME properties

Christiansen, Elisabeth,Due-Hansen, Maria E.,Urban, Christian,Grundmann, Manuel,Schr?der, Ralf,Hudson, Brian D.,Milligan, Graeme,Cawthorne, Michael A.,Kostenis, Evi,Kassack, Matthias U.,Ulven, Trond

, p. 6624 - 6628 (2012)

FFA1 (GPR40) is a new target for treatment of type 2 diabetes. We recently identified the potent FFA1 agonist TUG-469 (5). Inspired by the structurally related TAK-875, we explored the effects of a mesylpropoxy appendage on 5. The appendage significantly lowers lipophilicity and improves metabolic stability while preserving potency, resulting in discovery of the potent FFA1 agonist 13.

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