1390672-84-0

Basic information

• Product Name: (S)-di-tert-butyl 2-{3-[(S)-2-phenyl-2-[(S)-pyrrolidine-2-carboxamido]ethyl]thioureido}succinate
• Synonyms: (S)-di-tert-butyl 2-{3-[(S)-2-phenyl-2-[(S)-pyrrolidine-2-carboxamido]ethyl]thioureido}succinate
• CAS NO: 1390672-84-0
• Molecular Weight: 520.693
• Mol File: 1390672-84-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-di-tert-butyl 2-{3-[(S)-2-phenyl-2-[(S)-pyrrolidine-2-carboxamido]ethyl]thioureido}succinate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-di-tert-butyl 2-{3-[(S)-2-phenyl-2-[(S)-pyrrolidine-2-carboxamido]ethyl]thioureido}succinate(1390672-84-0)
• EPA Substance Registry System: (S)-di-tert-butyl 2-{3-[(S)-2-phenyl-2-[(S)-pyrrolidine-2-carboxamido]ethyl]thioureido}succinate(1390672-84-0)

Safety Data

• Hazardous Substances Data: 1390672-84-0(Hazardous Substances Data)

Upstream product

• 137102-29-5 (S)-(+)-1-<(butoxycarbonyl)amino>-1-phenylethyl azide 
• 110143-62-9 (S)-(+)-<2-<(methylsulfonyl)oxy>-1-phenylethyl>carbamic acid 1,1-dimethylethyl ester 
• 144125-06-4 (S)-2-azido-1-phenyl-ethylamine 
• 190393-65-8 (S)-2-<(benzyloxycarbonyl)amino>-2-phenyl ethyl azide 
• 130406-36-9 ((S)-2-Amino-1-phenyl-ethyl)-carbamic acid benzyl ester 
• 2900-27-8 (2S)-2-[(tert-butoxycarbonyl)amino]-2-phenylethanoic acid 
• 117049-14-6 tert-butyl N-[(1S)-2-hydroxy-1-phenylethyl]carbamate 
• 1390672-83-9 (S)-di-tert-butyl 2-{3-[(S)-2-((S)-1-(((9H-fluoren-9-yl)methoxy)carbonyl)pyrrolidine-2-carboxamido)-2-phenylethyl]thioureido}succinate 
• 1390672-82-8 C₂₈H₂₉N₃O₃*ClH 
• 1390672-81-7 (S)-(9H-fluoren-9-yl)methyl 2-[(S)-2-(tert-butoxycarbonylamino)-1-phenylethylcarbamoyl]pyrrolididne-1-carboxylate 
• 943322-87-0 tert-butyl N-[(2S)-2-amino-2-phenylethyl]carbamate 
• 1374635-42-3 tert-butyl N-[(2S)-2-(benzyloxycarbonylamino)-2-phenyl-ethyl]carbamate 

Relevant articles and documents

A tripeptide-like prolinamide-thiourea as an aldol reaction catalyst

A tripeptide-like prolinamide-thiourea catalyst with (S)-proline, (1S,2S)-diphenylethylenediamine and (S)-di-tert-butyl aspartate as building blocks provides the products of the reaction between ketones and aromatic aldehydes in high to quantitative yields and high stereoselectivities (up to 99:1 dr and 99% ee). Both the chiral centers of the diamine unit are essential, while the thiourea hydrogen originating from the amine and the amide hydrogen play a predominant role for the catalyst efficiency.