139068-53-4

Upstream product

• 6506-86-1 ethyl (6-amino-4-chloro-5-nitropyridin-2-yl)carbamate 
• 139068-50-1 ethyl <(1S,2R)-6-amino-4-<<2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl>amino>-5-nitropyridin-2-yl>carbamate 

Downstream Products

• 139068-55-6 ethyl <(S)-5-amino-1,2-dihydro-3-(4-hydroxyphenyl)-2-methylpyrido<3,4-b>pyrazin-7-yl>carbamate 
• 646073-32-7 ethyl <(S)-6-amino-4-<<2-(4-hydroxyphenyl)-1-methyl-2-oxoethyl>amino>-5-nitropyridin-2-yl>carbamate oxime 

Relevant academic research and scientific papers

Antimitotic agents. Chiral isomers of ethyl [5-amino-1,2-dihydro-3-(4- hydroxyphenyl)-2-methylpyrido[3,4-b]pyrazin-7-yl]carbamate

Metabolism studies with ethyl [5-amino-1,2-dihydro-2-methyl-3- phenylpyrido[3,4-b]pyrazin-7-yl]carbamate (1) in mice were reported previously to give a hydroxylated metabolite, which was methylated to give a methoxy derivative. The metabolite and its deri