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1-(2-chloroethyl)-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-1-nitrosourea, commonly known as lomustine, is a chemotherapy drug that belongs to the alkylating agents class. It is characterized by its ability to disrupt the DNA of cancer cells, causing cell death and effectively treating various types of cancer, particularly brain tumors.

13907-54-5

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13907-54-5 Usage

Uses

Used in Oncology:
Lomustine is utilized as an anticancer agent, specifically for the treatment of brain tumors such as malignant gliomas. It is effective in interfering with the DNA of cancer cells, leading to their death and providing a therapeutic approach to combat cancer progression.
Additionally, lomustine is used in combination with other cancer treatments to enhance the overall efficacy of the treatment regimen. However, it is important to note that lomustine can also cause damage to healthy cells, resulting in potential side effects such as bone marrow suppression and an increased risk of infection.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, lomustine is used as a key component in the development of oral chemotherapy medications. It is typically administered in the form of a capsule, allowing for convenient and effective delivery of the drug to patients. The pharmaceutical industry continues to research and develop novel drug delivery systems to improve the bioavailability and therapeutic outcomes of lomustine, aiming to minimize side effects and enhance its overall effectiveness in cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 13907-54-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,0 and 7 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 13907-54:
(7*1)+(6*3)+(5*9)+(4*0)+(3*7)+(2*5)+(1*4)=105
105 % 10 = 5
So 13907-54-5 is a valid CAS Registry Number.

13907-54-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chloroethyl)-3-(2,4-dioxo-1H-pyrimidin-5-yl)-1-nitrosourea

1.2 Other means of identification

Product number -
Other names 1-(2-chloroethyl)-3-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-1-nitrosourea

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13907-54-5 SDS

13907-54-5Upstream product

13907-54-5Downstream Products

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