13908-14-0

Basic information

• Product Name: 1-(2-chloroethyl)-3-(3-methylcyclohexyl)urea
• Synonyms: 1-(2-Chloroethyl)-3-(3-methylcyclohexyl)urea; urea, N-(2-chloroethyl)-N'-(3-methylcyclohexyl)-
• CAS NO: 13908-14-0
• Molecular Formula: C₁₀H₁₉ClN₂O
• Molecular Weight: 218.7237
• Mol File: 13908-14-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 383.7°C at 760 mmHg
• Flash Point: 185.9°C
• Density: 1.08g/cm³
• Vapor Pressure: 4.31E-06mmHg at 25°C
• Refractive Index: 1.494
• CAS DataBase Reference: 1-(2-chloroethyl)-3-(3-methylcyclohexyl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-chloroethyl)-3-(3-methylcyclohexyl)urea(13908-14-0)
• EPA Substance Registry System: 1-(2-chloroethyl)-3-(3-methylcyclohexyl)urea(13908-14-0)

Safety Data

• Hazardous Substances Data: 13908-14-0(Hazardous Substances Data)

Usage

General Description

1-(2-chloroethyl)-3-(3-methylcyclohexyl)urea, also known as chloroethyl cyclohexylurethane, is a synthetic chemical compound with potential antineoplastic and apoptotic activities. It belongs to the class of alkylating agents and is used in cancer treatments to inhibit cell proliferation and induce cell death in cancerous cells. The compound works by forming covalent bonds with DNA, ultimately leading to DNA damage and programmed cell death. It is also being researched for its potential use in combination therapy with other chemotherapeutic drugs to enhance treatment efficacy. Overall, 1-(2-chloroethyl)-3-(3-methylcyclohexyl)urea shows promise as a valuable tool in the fight against cancer and warrants further investigation in clinical settings.

Upstream product

• 1943-83-5 2-chloroethyl isothiocyanate 
• 6850-35-7 3-methylcyclohexan-1-amine 

Downstream Products

• 13991-72-5 1-(2-chloroethyl)-1-nitroso-3-(3-methylcyclohexyl)urea 

Relevant articles and documents

The synthesis of potential anticancer agents. XXXVI. N-nitrosoureas. II. Haloalkyl derivatives.

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