13908-44-6 Usage
Classification
Platinum-based chemotherapy drug
Usage
Treatment of various types of cancer
Ovarian, lung, and testicular cancer
Mechanism of action
Damages the DNA within cancer cells
Ultimately leading to their destruction
Administration
Intravenous
Combination therapy
Often used with other chemotherapy medications
Common side effects
Nausea
Vomiting
Decreased platelet count
Decreased white blood cell count
Serious and potentially life-threatening side effects
Possible
Supervision
Should only be used under the guidance of a qualified healthcare provider
Check Digit Verification of cas no
The CAS Registry Mumber 13908-44-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,0 and 8 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 13908-44:
(7*1)+(6*3)+(5*9)+(4*0)+(3*8)+(2*4)+(1*4)=106
106 % 10 = 6
So 13908-44-6 is a valid CAS Registry Number.
13908-44-6Relevant articles and documents
Reactions of o-Aminonitriles with Isocyanates. 1. A Two-Step Synthesis of 2,6-Dihydroimidazoquinazolin-5-(3H)one
Papadopoulos, Eleftherios Paul
, p. 1553 - 1558 (2007/10/02)
The reaction of anthranilonitrile with 2-chloroethyl isocyanate yields 2-benzonitrile (6) which, upon heating, or treatment with base, undergoes a double cyclization to form 2,6-dihydroimidazoquinazolin-5-(3H)one (8) in excellent yield.When heated with hydrochloric acid, 6 is converted initially into 2-(2-chloroethylamino)-4H-benzoxazin-4-one (18) and further into 3-(2-chloroethyl)-2,4-(1H,3H)quinazolinedione (15).The acid-catalyzed reaction of 2,3-dihydro-5H-oxazoloquinazolin-5-one (14) with nucleophilic reagents yields 3-substituted 2,4-(1H,3H)quinazolinediones.