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13908-44-6

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13908-44-6 Usage

Classification

Platinum-based chemotherapy drug

Usage

Treatment of various types of cancer
Ovarian, lung, and testicular cancer

Mechanism of action

Damages the DNA within cancer cells
Ultimately leading to their destruction

Administration

Intravenous

Combination therapy

Often used with other chemotherapy medications

Common side effects

Nausea
Vomiting
Decreased platelet count
Decreased white blood cell count

Serious and potentially life-threatening side effects

Possible

Supervision

Should only be used under the guidance of a qualified healthcare provider

Check Digit Verification of cas no

The CAS Registry Mumber 13908-44-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,0 and 8 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 13908-44:
(7*1)+(6*3)+(5*9)+(4*0)+(3*8)+(2*4)+(1*4)=106
106 % 10 = 6
So 13908-44-6 is a valid CAS Registry Number.

13908-44-6Relevant articles and documents

Reactions of o-Aminonitriles with Isocyanates. 1. A Two-Step Synthesis of 2,6-Dihydroimidazoquinazolin-5-(3H)one

Papadopoulos, Eleftherios Paul

, p. 1553 - 1558 (2007/10/02)

The reaction of anthranilonitrile with 2-chloroethyl isocyanate yields 2-benzonitrile (6) which, upon heating, or treatment with base, undergoes a double cyclization to form 2,6-dihydroimidazoquinazolin-5-(3H)one (8) in excellent yield.When heated with hydrochloric acid, 6 is converted initially into 2-(2-chloroethylamino)-4H-benzoxazin-4-one (18) and further into 3-(2-chloroethyl)-2,4-(1H,3H)quinazolinedione (15).The acid-catalyzed reaction of 2,3-dihydro-5H-oxazoloquinazolin-5-one (14) with nucleophilic reagents yields 3-substituted 2,4-(1H,3H)quinazolinediones.

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