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1-(2-fluoroethyl)-3-cyclohexyl-1-nitrosourea is a chemical compound that belongs to the class of nitrosoureas, which are alkylating agents widely used in cancer chemotherapy. This specific compound contains a fluoroethyl group and a cyclohexyl group attached to a nitrosourea functional group. Nitrosoureas are known for their ability to alkylate DNA, leading to the inhibition of DNA replication and ultimately cell death.
Used in Pharmaceutical Industry:
1-(2-fluoroethyl)-3-cyclohexyl-1-nitrosourea is used as an anticancer agent for its alkylating properties that can inhibit DNA replication in cancer cells, leading to cell death. It is particularly effective against brain tumors and Hodgkin's lymphoma.
Used in Cancer Research:
1-(2-fluoroethyl)-3-cyclohexyl-1-nitrosourea is used in combination therapy studies to explore its potential synergistic effects with other cancer treatments, aiming to enhance chemo-sensitivity and efficacy in resistant cases.
Used in Drug Development:
1-(2-fluoroethyl)-3-cyclohexyl-1-nitrosourea is utilized in the development of novel drug delivery systems to improve its bioavailability and therapeutic outcomes, as well as to mitigate potential side effects caused by its alkylating properties on normal cells.

13908-93-5

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13908-93-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 13908-93-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,0 and 8 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 13908-93:
(7*1)+(6*3)+(5*9)+(4*0)+(3*8)+(2*9)+(1*3)=115
115 % 10 = 5
So 13908-93-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H16FN3O2/c10-6-7-13(12-15)9(14)11-8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14)

13908-93-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-cyclohexyl-1-(2-fluoroethyl)-1-nitrosourea

1.2 Other means of identification

Product number -
Other names N3-(cyclohexyl)-N1-(2-fluoroethyl)-N1-nitrosourea

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13908-93-5 SDS

13908-93-5Downstream Products

13908-93-5Relevant academic research and scientific papers

1,2,2,2-Tetrachloroethyl Carbamates: Versatile Intermediates for the Synthesis of N-Nitrosoureas

Barcelo, Gerard,Senet, Jean-Pierre,Sennyey, Gerard

, p. 1027 - 1029 (2007/10/02)

1,2,2,2-Tetrachloroethyl carbamates 3 were prepared by the reaction of 1,2,2,2-tetrachloroethyl carbonochloridate with amines.Carbamates 3 were then nitrosated and reacted with amines to yield N-nitrosoureas.

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