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1-(2-chloroethyl)-3-cyclopentyl-1-nitroso-urea, also known as CCNU or lomustine, is a chemical compound that serves as a chemotherapy medication. It is characterized by its ability to disrupt the growth and reproduction of cancer cells, leading to their destruction. As an alkylating agent, CCNU forms strong covalent bonds with DNA, which prevents replication and transcription, ultimately inhibiting cancer cell proliferation and inducing cell death.

13909-03-0

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13909-03-0 Usage

Uses

Used in Oncology:
1-(2-chloroethyl)-3-cyclopentyl-1-nitroso-urea is used as a chemotherapy agent for the treatment of various types of cancer, including brain tumors and Hodgkin's lymphoma. Its application is based on its effectiveness in disrupting the growth and reproduction of cancer cells, leading to their destruction.
The use of CCNU in chemotherapy is due to its alkylating properties, which allow it to form strong covalent bonds with DNA, thereby preventing DNA replication and transcription. This action inhibits cancer cell proliferation and results in cell death.
However, it is important to note that CCNU can also have toxic effects on the bone marrow, potentially leading to decreased blood cell production. As with any chemotherapy drug, CCNU should be used under medical supervision, and patients may experience side effects such as nausea, vomiting, and hair loss.

Check Digit Verification of cas no

The CAS Registry Mumber 13909-03-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,9,0 and 9 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 13909-03:
(7*1)+(6*3)+(5*9)+(4*0)+(3*9)+(2*0)+(1*3)=100
100 % 10 = 0
So 13909-03-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H14ClN3O2/c9-5-6-12(11-14)8(13)10-7-3-1-2-4-7/h7H,1-6H2,(H,10,13)

13909-03-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chloroethyl)-3-cyclopentyl-1-nitrosourea

1.2 Other means of identification

Product number -
Other names Urea,N-(2-chloroethyl)-N'-cyclopentyl-N-nitroso

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:13909-03-0 SDS

13909-03-0Downstream Products

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