13909-21-2

Basic information

• Product Name: 1-(2-chloroethyl)-3-(3-methoxyphenyl)-1-nitrosourea
• CAS NO: 13909-21-2
• Molecular Formula: C₁₀H₁₂ClN₃O₃
• Molecular Weight: 257.6736
• Mol File: 13909-21-2.mol
• Article Data: 1

Chemical Properties

• Density: 1.32g/cm³
• Refractive Index: 1.567
• CAS DataBase Reference: 1-(2-chloroethyl)-3-(3-methoxyphenyl)-1-nitrosourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-chloroethyl)-3-(3-methoxyphenyl)-1-nitrosourea(13909-21-2)
• EPA Substance Registry System: 1-(2-chloroethyl)-3-(3-methoxyphenyl)-1-nitrosourea(13909-21-2)

Safety Data

• Hazardous Substances Data: 13909-21-2(Hazardous Substances Data)

Usage

General Description

1-(2-chloroethyl)-3-(3-methoxyphenyl)-1-nitrosourea is a chemical compound that belongs to the class of nitrosoureas, which are known for their anti-cancer properties. This specific compound is a derivative of nitrosourea and consists of a nitrosocarbamoyl group and an ethylchloride group, as well as a methoxyphenyl group. It is commonly used as a chemotherapy drug to treat certain types of brain tumors, such as glioblastoma multiforme and astrocytoma. The compound works by inhibiting the growth of cancer cells and disrupting their DNA replication and repair processes. It is typically administered orally or intravenously and is known to have various side effects, including nausea, vomiting, and bone marrow suppression.

Upstream product

• 536-90-3 m-Anisidine 
• 13908-42-4 1-(2-chloro-ethyl)-3-(3-methoxy-phenyl)-urea 

Relevant articles and documents

The synthesis of potential anticancer agents. XXXVI. N-nitrosoureas. II. Haloalkyl derivatives.

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