1391-06-6

Basic information

• Product Name: CONALBUMIN
• Synonyms: CONALBUMIN;CONALBUMIN CHICKEN;CONALBUMIN IRON COMPLEX;OVOTRANSFERRIN;OVOTRANSFERRIN CHICKEN;OVOTRANSFERRIN IRON COMPLEX;Conalbumin chicken egg white;conalbumin from chicken egg white cell*culture te
• CAS NO: 1391-06-6
• Molecular Weight: 0
• EINECS: 215-727-0
• Mol File: 1391-06-6.mol
• Article Data: 0

Chemical Properties

• Appearance: white crystalline powder
• Storage Temp.: −20°C
• Stability: Stable. Incompatible with strong oxidizing agents.
• CAS DataBase Reference: CONALBUMIN(CAS DataBase Reference)
• NIST Chemistry Reference: CONALBUMIN(1391-06-6)
• EPA Substance Registry System: CONALBUMIN(1391-06-6)

Safety Data

• Hazard Codes: Xn
• Statements: 42/43
• Safety Statements: 36
• WGK Germany: 3
• F: 3-10
• Hazardous Substances Data: 1391-06-6(Hazardous Substances Data)

Usage

Description

Conalbumin, also known as ovotransferrin, is a monomeric glycoprotein that constitutes approximately 13% of the albumin found in egg white. It is an iron-carrying protein with identical 19-amino-acid leader sequences to serum transferrin, which are removed during protein maturation. Conalbumin is a white crystalline powder and is known for its stable iron complex, which remains intact under various chemical and physical treatments.

Uses

Used in Cell Culture:
Conalbumin is used as a constituent of Leibovitz 15 (L15) medium for the preparation of primary neuronal cultures. It aids in the growth and maintenance of these cells in the laboratory.
Used in Surface Adsorption Studies:
Conalbumin is utilized to study its adsorption property on a metal surface in the presence of an external electric potential. This application helps in understanding the interaction between the protein and metal surfaces, which can be crucial in various industrial and medical applications.
Used in Chromatography:
Conalbumin is employed to determine its adsorption isotherms in anion exchange chromatography through multivariate analysis. This helps in optimizing the separation and purification processes involving this protein.
Used in Microplate Assays:
Conalbumin from chicken egg white serves as an ovotransferrin standard in 96-well microplate assays to investigate ovotransferrin-like activity in the plasma of wild birds.
Used in Osteoclastogenesis Research:
Conalbumin is used to examine its effects on osteoclastogenesis, which is the process of bone resorption by osteoclasts. This application is essential for understanding the role of conalbumin in bone metabolism and its potential implications in bone-related diseases.
Used in Aqueous Two-Phase Systems:
Conalbumin is utilized to study its partitioning in aqueous two-phase systems, which can provide insights into the protein's behavior in different environments and its potential applications in biotechnology and pharmaceutical industries.

Biochem/physiol Actions

Conalbumin facilitates the transport of iron to the developing embryo. It exhibits anti-microbial activity thus, conalbumin is used in various applications such as infant formula ingredient, a food additive, and an antimicrobial agent for enhancing animal health. In addition, it also acts as an antifungal, antiviral, anticancer, antioxidative, antihypertensive and immunoregulatory agent.

Related news

Thermodynamic studies of partitioning behavior of lysozyme and CONALBUMIN (cas 1391-06-6) in aqueous two-phase systems09/03/2019

The objective of this study was to determine the thermodynamic parameters (ΔtrG, ΔtrH and ΔtrS) associated with lysozyme and conalbumin partitioning in aqueous two-phases systems (ATPS). Influence of salt type and polyethylene glycol (PEG) concentrations on the partition coefficient of lysozy...detailed