1391014-00-8Relevant articles and documents
Organocatalyzed anodic oxidation of aldehydes
Finney, Eric E.,Ogawa, Kelli A.,Boydston, Andrew J.
, p. 12374 - 12377 (2012)
A method for the catalytic formation of electroauxiliaries and subsequent anodic oxidation has been developed. The process interfaces N-heterocyclic carbene-based organocatalysis with electro-organic synthesis to achieve direct oxidation of catalytically generated electroactive intermediates. We demonstrate the applicability of this method as a one-pot conversion of aldehydes to esters for a broad range of aldehyde and alcohol substrates. Furthermore, the anodic oxidation reactions are very clean, producing only H2 gas as a result of cathodic reduction.