1391432-51-1Relevant articles and documents
Novel BACE1 inhibitors possessing a 5-nitroisophthalic scaffold at the P2 position
Hamada, Yoshio,Nakanishi, Tomoya,Suzuki, Kenji,Yamaguchi, Ryoji,Hamada, Takashi,Hidaka, Koushi,Ishiura, Shoichi,Kiso, Yoshiaki
, p. 4640 - 4644 (2012)
Recently, we reported substrate-based pentapeptidic BACE1 inhibitors possessing a hydroxymethylcarbonyl isostere as a substrate transition-state mimic. These inhibitors showed potent inhibitory activities in enzymatic and cell assays. We also designed and
