139149-06-7

Upstream product

• 3470-50-6 6-Hydroxy-1-tetralone 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 950505-27-8 difluoro-[1-hydroxy-6-(4-methoxy-benzyloxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-acetic acid ethyl ester 
• 950505-23-4 (R/S)-[6-(2'-butoxy-5'-methyl-biphenyl-4-ylmethoxy)-1,2,3,4-tetrahydro-naphthalen-1-yl]-acetic acid ethyl ester 
• 950505-77-8 (R/S)-[6-((E)-2-biphenyl-4-yl-vinyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]-acetic acid ethyl ester 
• 950505-78-9 (R/S)-[6-(1-biphenyl-4-yl-vinyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]-acetic acid ethyl ester 
• 950505-81-4 {6-[(E)-2-(4-trifluoromethyl-phenyl)-vinyl]-1,2,3,4-tetrahydro-naphthalen-1-yl}-acetic acid ethyl ester 
• 950505-79-0 (R/S)-[6-((E)-2-biphenyl-4-yl-vinyl)-1,2,3,4-tetrahydro-naphthalen-1-yl]-acetic acid 
• 950505-25-6 6-(4-methoxybenzyloxy)-2-methyl-3,4-dihydronaphthalen-1(2H)-one 
• 929713-42-8 [6-(4-methoxy-benzyloxy)-3,4-dihydro-2H-naphthalen-(1E)-ylidene]-acetic acid 

Relevant academic research and scientific papers

Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders

The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I: where the definitions of the variables Q, L1, L2, M, X, L3, and A are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.

BICYCLIC CARBOXYLIC ACID DERIVATIVES USEFUL FOR TREATING METABOLIC DISORDERS

Compounds having the general formula I and/or the general formula II are useful, for example, for treating metabolic disorders in a subject formula (I) (II) where the variables are provided herein. Compositions and methods for using the compounds for preparing medicaments and for treating metabolic disorders such as, for instance, type II diabetes are disclosed.