1391611-33-8

Basic information

• Product Name: C₂₀H₁₉N₃O₂
• CAS NO: 1391611-33-8
• Molecular Weight: 333.39
• Mol File: 1391611-33-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₁₉N₃O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₁₉N₃O₂(1391611-33-8)
• EPA Substance Registry System: C₂₀H₁₉N₃O₂(1391611-33-8)

Safety Data

• Hazardous Substances Data: 1391611-33-8(Hazardous Substances Data)

Upstream product

• 1022-46-4 2-phenyl-4H-3,1-benzoxazin-4-one 
• 6484-25-9 4-chloro-2-phenylquinazoline 
• 498-95-3 nipecotic acid 

Relevant articles and documents

Design, synthesis and biological evaluation of novel quinazoline derivatives as potential anti-cancer agents

Twenty-two quinazoline derivatives have been synthesised and examined for their anti-tumour activity against three tumour cell lines, namely human breast cancer cell line (MCF-7), human cervical cancer cell line (HeLa) and human hepatoma cell line (HepG2). Twelve of the tested compounds have shown promising anti-tumour activity with an IC50 range of 5.09.7 g/mL. Regarding the spectrum of activity, five compounds exhibited interesting anti-proliferative properties against the three tested cell lines comparable to the reference drug (dasatinib).