139165-52-9

Upstream product

• 103-30-0 (E)-1,2-diphenyl-ethene 
• 73210-14-7 N-chloro-N-sodio-tert-butylcarbamate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 102565-20-8 (R*,S*)-2-azido-1,2-diphenylethanol 
• 4248-19-5 tert-butyl carbazate 
• 530-36-9 (1R,2R)-2-amino-1,2-diphenylethane-1-ol 
• 142560-68-7 (1R,2S)-(+)-tert-butyl 2-hydroxy-1,2-diphenylethylcarbamate 
• 23204-71-9 (4R,5R)-trans-4,5-diphenyl-2-oxazolidinone 

Downstream Products

• 105748-30-9 C₄₅H₃₁NO₃ 
• 23204-71-9 (4R,5R)-trans-4,5-diphenyl-2-oxazolidinone 
• 86286-50-2 (4R,5S)-4,5-diphenyl-1,3-oxazolidin-2-one 
• 39664-87-4 dl-threo-1,2-diphenyl-2-hydroxethylamine 

Relevant academic research and scientific papers

Dynamic kinetic resolution in the stereoselective synthesis of 4,5-diaryl cyclic sulfamidates by using chiral rhodium-catalyzed asymmetric transfer hydrogenation

The dynamic kinetic resolution of 4,5-diaryl cyclic sulfamidate imines was achieved via asymmetric transfer hydrogenation using a HCO2H/Et 3N mixture as the hydrogen source and chiral Rh catalysts (R,R)- or (S,S)-RhCl(TsDPEN)Cp* affo

From vicinal azido alcohols to Boc-amino alcohols or oxazolidinones, with trimethylphosphine and Boc2O or CO2

A practical solution to the problem of converting directly 1,2-azido alcohols to Boc-amino alcohols, without recourse to catalytic hydrogenation, involves the use of Me3P/Boc2O in THF (or CH2Cl2) and aqueous NaOH at rt (90-98% yields). The same azido alcohols can be converted in one-pot to the corresponding oxazolidinones with Boc2O/DMAP/Me3P or even better with CO2 and Me3P under basic catalysis (91-96% yields).

Facile inversion of configuration of N-Boc-β-aminoalcohols via S(N)2 cyclization to oxazolidinones

Oxazolidinones are obtained by the cyclization of mesylates derived from N-Boc-β-Aminoalcohols. Hydrolysis of the N-Boc-Oxazolidinones regenerates the protected aminoalcohols with inverted configuration at the hydroxy group. (C) 2000 Elsevier Science Ltd.

SYNTHESES ASYMETRIQUES ET SYNTHESES ASYMETRIQUES POTENTIELLES D' α-AMINO ALCOOLS: HYDROXYAMINATION D' OLEFINES PAR LA METHODE DE SHARPLESS.

Optically active α-amino alcohols have been synthesized by Sharpless' method with (-)-10,11-dihydroquinine 2 and (R)-(-)-pantolactone 8 as chiral inducers.Five secondary (dl) alcohols : 3,4,5,6,7 and (dl) 2-hydroxyheptahelicene 1 have also been used to prepare the intermediate diastereomeric (dl) α-hydroxy carbamates 9.The highest inductions were obtained with (-)-10,11-dihydroquinine and (E)-stilbene (e.e. >/=98percent and with (dl) 2-hydroxyheptahelicene and (E)-stilbene (d.e. >/=98percent).