139178-82-8

Upstream product

• 37571-13-4 Boc-Leu-Lys(Z)-OH 
• 593-51-1 methylamine hydrochloride 
• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 37571-12-3 N-tert-butoxycarbonyl-L-leucyl-L-(N-ε-benzyloxycarbonyl)lysine methyl ester 
• 27894-50-4 methyl (2S)-2-amino-6-{[(benzyloxy)carbonyl]amino}hexanoate hydrochloride 

Relevant academic research and scientific papers

A single point chiral inversion that selforganizes a randomcoil peptide. Apolar solvent conformation of Boc-(L/D)-Glu-Ala-Leu-LysNHMe

The tetrapeptide Boc-L-Glu-Ala-Leu-LysNHMe (1) reveals a random coil conformation, based on its Glu(γ) and Lys(ε) methylene proton aniosotropic shift, GluNH chemical shift, NOEs in the chloroform-DMSO (6:1), and its amide proton temperature coefficients in DMSO, while on similar considerations, the diastereomer Boc-D-Glu-Ala-Leu-LysNHMe (2) is characterized as a highly ordered 3/10 type distorted protohelix with a remarkably stable intramolecular salt bridge under these solvent conditions.