1391938-75-2

Upstream product

• 1356410-74-6 N-(4-bromo-2-methoxy-phenyl)-guanidine 
• 1391938-66-1 methyl (6E)-6-[(dimethylamino)methylidene]-1-methyl-7-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxylate 
• 1391938-59-2 methyl 1-methyl-7-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxylate 

Downstream Products

• 1391938-16-1 2-[(4-bromo-2-methoxyphenyl)amino]-N-[(1S)-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1-phenylethyl]-9-methyl-6,9-dihydro-5H-pyrrolo[3,2-h]quinazoline-7-carboxamide 
• 1391938-83-2 2-[(4-bromo-2-methoxyphenyl)amino]-9-methyl-6,9-dihydro-5H-pyrrolo[3,2-h]quinazoline-7-carboxylic acid 
• 1391937-99-7 2-[(4-bromo-2-methoxyphenyl)amino]-N-(2,6-diethylphenyl)-9-methyl-6,9-dihydro-5H-pyrrolo[3,2-h]quinazoline-7-carboxamide 
• 1391938-03-6 N-(2,6-diethylphenyl)-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-9-methyl-6,9-dihydro-5H-pyrrolo[3,2-h]quinazoline-7-carboxamide 

Relevant academic research and scientific papers

TRICYCLIC PYRROLO DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS KINASE INHIBITORS

The present invention relates to tricyclic pyrrolo derivatives of Formula (I), which modulate the activity of protein kinases and are therefore useful in treating diseases caused by dysregulated protein kinase activity. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing such these compounds or the pharmaceutical compositions containing them.