1392014-16-2Relevant academic research and scientific papers
Expedient N-arylation for the synthesis of 2-arylamino-3-cyanopyridines using ionic copper(I) complex as a catalyst
Zhang, Min,Xiong, Biao,Wang, Ting,Wang, Xiaoting,Yan, Fengxia,Ding, Yuqiang
, p. 1393 - 1404 (2012)
The N-arylation of 2-amino-3-cyanopyridines is firstly described by using ionic copper(I) complex (Phen)2Cu+BF4 - (phen = 1,10-phenanthroline) as an efficient catalyst. The synthetic protocol can be applied to synthesize a wide range of 2-arylamino-3-cyanopyridine products in good to excellent isolated yields. The resulted products are potentially building blocks for further preparation of biologically interesting products or useful ligands for metal catalysis.
