139209-88-4

Basic information

• Product Name: (R)-5-Hydroxy-hexanoic acid ((R)-1-phenyl-ethyl)-amide
• CAS NO: 139209-88-4
• Molecular Weight: 235.326
• Mol File: 139209-88-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-5-Hydroxy-hexanoic acid ((R)-1-phenyl-ethyl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-5-Hydroxy-hexanoic acid ((R)-1-phenyl-ethyl)-amide(139209-88-4)
• EPA Substance Registry System: (R)-5-Hydroxy-hexanoic acid ((R)-1-phenyl-ethyl)-amide(139209-88-4)

Safety Data

• Hazardous Substances Data: 139209-88-4(Hazardous Substances Data)

Upstream product

• 10048-32-5 (S)-parasorbic acid 
• 29736-80-9 3,5-dioxohexanoic acid methyl ester 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 16320-13-1 (S)-6-methyl-tetrahydro-pyran-2-one 

Relevant articles and documents

Asymmetric Hydrogenation of Methyl 3,5-Dioxohexanoate Catalyzed by Ru-binap Complex: A Short Step Asymmetric Synthesis of Dihydro-6-methyl-2H-pyran-2-one

Hydrogenation of methyl 3,5-dioxohexanoate 3 using Ru2Cl4((R) or (S)-binap)2(NEt3) as the catalyst gave dominantly anti 3,5-dihydroxyester 9, which was then converted into unsaturated lactone 4.The pathway of the hydrogenation reaction was also investigated. Key words: β,δ-diketonester; Ru-binap catalyst; asymmetric hydrogenation; asymmetric synthesis; lactone.