1392098-02-0

Basic information

• Product Name: C₄₄H₆₄O₈Si₂
• CAS NO: 1392098-02-0
• Molecular Weight: 777.158
• Mol File: 1392098-02-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₄₄H₆₄O₈Si₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₄₄H₆₄O₈Si₂(1392098-02-0)
• EPA Substance Registry System: C₄₄H₆₄O₈Si₂(1392098-02-0)

Safety Data

• Hazardous Substances Data: 1392098-02-0(Hazardous Substances Data)

Upstream product

• 2873-29-2 D-glucal triacetate 
• 13265-84-4 D-glucal 
• 262266-33-1 1,5-anhydro-2-deoxy-4,6-O-bis(tert-butylsilylidene)-3-O-triisopropylsilyl-D-arabino-hex-1-enitol 
• 191593-14-3 4,6-O-di(tert-butyl)silanediyl-D-glucal 
• 24131-31-5 3,5-dibenzyloxybenzyl alcohol 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 58605-10-0 methyl 3,5-bis(benzyloxy)benzoate 
• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 
• 1392097-98-1 2-[1,5-anhydro-2-deoxy-4,6-O-(di-tert-butylsilylidene)-3-O-triisopropylsilyl-D-arabinohex-1-enitol-3,5-bis(benzyloxy)]-benzyl alcohol 
• 1392097-95-8 C₄₉H₇₂O₈Si₂ 
• 1392097-94-7 1-C-dimethylhydroxysilyl-3-O-triisopropylsilyl-4,6-O-di-(tert-butyl)silanediyl-D-glucal 
• 1392097-93-6 1-C-dimethylsilyl-3-O-triisopropylsilyl-4,6-O-di-(tert-butyl)silanediyl-D-glucal 
• 934243-67-1 2-iodo-3,5-bis(phenylmethoxy)-(2',2'-dimethylpropanoyloxymethyl)benzene 
• 934243-80-8 2-iodo-3,5-bis(phenylmethoxy)benzenemethanol 

Relevant articles and documents

Synthesis and antifungal properties of papulacandin derivatives

Derivatives of an antifungal agent that targets the β-(1,3)-D-glucan synthase, papulacandin D, were synthesized and tested for activity. The papulacandin D structure contains a challenging benzannulated spiroketal unit, which is introduced in a palladiumcatalyzed cross-coupling reaction of a glycal silanolate and an aryl iodide followed by an oxidative spiroketalization. Four different variants were made, differing in the nature of the acyl side chain with respect to the length, and in the number and stereochemistry of the double bonds. Moderate biological activity was observed for the derivatives with a side chain based on palmitic acid and linoleic acid.