1392104-07-2

Upstream product

• 1392104-16-3 6-(tert-butyldiphenylsilyloxy)-(5S)-5-hydroxyl-N-methoxy-N-methylhexanamide 
• 1392104-08-3 (5S)-5-(tert-butyldimethylsilyloxy)-6-(tert-butyldiphenylsilyloxy)-N-methoxy-N-methylhexanamide 
• 1119-51-3 bromopentene 
• 175398-31-9 (S)-6-(tert-butyldiphenylsilyloxy)-5-hydroxyhexanoic acid δ-lactone 

Downstream Products

• 1392104-15-2 8-ethynyl-2-(tert-butyldiphenylsilyloxymethyl)-1,7-dioxaspiro[5.5]undecane 
• 1392104-37-8 14-(4-(8-((tert-butyldiphenylsilyloxy)methyl)-1,7-dioxaspiro[5.5]undecan-2-yl)-1H-1,2,3-triazol-1-yl)tetradecane-2,5-dione 
• 1392104-38-9 11-(4-(8-((tert-butyldiphenylsilyloxy)methyl)-1,7-dioxaspiro[5.5]undecan-2-yl)-1H-1,2,3-triazol-1-yl)undecan-2-one 
• 1392104-39-0 1-(10-(tert-butyldimethylsilyloxy)decyl)-4-((2S,6S,8S)-8-((tert-butyldiphenylsilyloxy)methyl)-1,7-dioxaspiro[5.5]undecan-2-yl)-1H-1,2,3-triazole 
• 1392104-40-3 methyl 6-(4-((2S,6S,8S)-8-((tert-butyldiphenylsilyloxy)methyl)-1,7-dioxaspiro[5.5]undecan-2-yl)-1H-1,2,3-triazol-1-yl)hexanoate 
• 1392104-41-4 1-(4-(4-((2S,6S,8S)-8-((tert-butyldiphenylsilyloxy)methyl)-1,7-dioxaspiro[5.5]undecan-2-yl)-1H-1,2,3-triazol-1-yl)phenyl)ethanone 
• 1392104-48-1 4-((2S,6S,8S)-8-((tert-butyldiphenylsilyloxy)methyl)-1,7-dioxaspiro[5.5]undecan-2-yl)-1-(3-methoxyphenyl)-1H-1,2,3-triazole 
• 1392104-10-7 (9S)-9-(tert-butyldimethylsilyloxy)-10-(tert-butyldiphenylsilyloxy)-5-(1,3-dioxolan-2-yl)decanal 
• 1392104-49-2 4-((2S,6S,8S)-8-((tert-butyldiphenylsilyloxy)methyl)-1,7-dioxaspiro[5.5]undecan-2-yl)-1-(3-nitrophenyl)-1H-1,2,3-triazole 
• 1392104-47-0 1-(4-(4-((2S,6S,8S)-8-(hydroxymethyl)-1,7-dioxaspiro[5.5]undecan-2-yl)-1H-1,2,3-triazol-1-yl)phenyl)ethanone 
• 1392104-50-5 ((2S,6S,8S)-8-(1-(3-methoxyphenyl)-1H-1,2,3-triazol-4-yl)-1,7-dioxaspiro[5.5]undecan-2-yl)methanol 
• 1392104-51-6 ((2S,6S,8S)-8-(1-(3-nitrophenyl)-1H-1,2,3-triazol-4-yl)-1,7-dioxaspiro[5.5]undecan-2-yl)methanol 
• 1392104-11-8 (3S,11S)-11-(tert-butyldimethylsilyloxy)-12-(tert-butyldiphenylsilyloxy)-7-(1,3-dioxolan-2-yl)dodec-1-yn-3-ol 
• 1392104-09-4 (10S)-10-(tert-butyldimethylsilyloxy)-11-(tert-butyldiphenylsilyloxy)-6-(1,3-dioxolan-2-yl)undec-1-ene 

Relevant academic research and scientific papers

Enantioselective synthesis of C-linked spiroacetal-triazoles as privileged natural product-like scaffolds

The enantioselective synthesis of novel C-linked spiroacetal-triazoles 10 is reported. The key step involves reaction of acetylenic spiroacetal 11 with several azides by the Copper-Catalysed Azide-Alkyne Cycloaddition (CuAAC). The biologically privileged spiroacetal scaffold 11 was prepared from silyl-protected Weinreb amide 19 using several reliable Grignard additions and a highly diastereoselective enzymatic kinetic resolution.