1392113-99-3Relevant articles and documents
6″-thioether tobramycin analogues: Towards selective targeting of bacterial membranes
Herzog, Ido M.,Green, Keith D.,Berkov-Zrihen, Yifat,Feldman, Mark,Vidavski, Roee R.,Eldar-Boock, Anat,Satchi-Fainaro, Ronit,Eldar, Avigdor,Garneau-Tsodikova, Sylvie,Fridman, Micha
, p. 5652 - 5656 (2012)
Amphiphilic tobramycin analogues with potent antibacterial activity against tobramycin-resistant bacteria were synthesized. Most analogues were found to be less prone to deactivation by aminoglycoside-modifying enzymes than tobramycin. These compounds tar