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1392191-23-9

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1392191-23-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1392191-23-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,2,1,9 and 1 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1392191-23:
(9*1)+(8*3)+(7*9)+(6*2)+(5*1)+(4*9)+(3*1)+(2*2)+(1*3)=159
159 % 10 = 9
So 1392191-23-9 is a valid CAS Registry Number.

1392191-23-9Downstream Products

1392191-23-9Relevant academic research and scientific papers

3-Aryl-4-methyl-2-quinolones Targeting Multiresistant Staphylococcus aureus Bacteria

Doleans-Jordheim, Anne,Veron, Jean-Baptiste,Fendrich, Olivier,Bergeron, Emmanuelle,Montagut-Romans, Adrien,Wong, Yung-Sing,Furdui, Bianca,Freney, Jean,Dumontet, Charles,Boumendjel, Ahcene

, p. 652 - 657 (2013/08/22)

The NorA efflux pump lowers intracellular fluoroquinolone concentrations by expelling antibiotics through the membrane of Staphylococcus aureus. We identified 3-aryl-4-methyl-2-quinolin-2-ones as compounds able to restore the activity of the NorA substrate, ciprofloxacin, against resistant S.aureus strains, and acting as efflux pump inhibitors (EPI). In particular, 5-hydroxy-7-methoxy-4-methyl-3-phenylquinolin-2-one (6c) presents both an EPI and an antimicrobial effect. Its efficacy and safety make it a potential candidate for further investigations.

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