139220-87-4Relevant academic research and scientific papers
Synthesis and antimicrobial activities of novel 10H-pyrido[3,2-b][1,4]benzo[b]thiazine ribofuranosides
Kumar, Neeraj,Singh, Girwar,Khatoon, Shabana,Yadav, Ashok K.
, p. 2015 - 2018 (2007/10/03)
The present communication describes the synthesis of 10-acetyl-9-chloro/9-bromo/8,9-dichloro-3-nitro-pyrido[3,2-b][1,4] benzo[b]thiazines 4, 10H-9-chloro/9-bromo/8,9-dichloro-3-nitro-pyrido[3,2-b][1,4]benzo[b]thiazines 5, 10H-9-chloro/9-bromo/8,9-dichloro-3-nitro-pyrido[3,2-b][1,4]benzo[b] thiazine-5-oxide 6. Compounds 5, on refluxing with β -D-ribofuranose-1-acetate-2,3,5-tribenzoate, affords N-(2′,3′ ,5′-tri-O-benzoyl-β-D-ribofuranosyl)-9-chloro/9-bromo/8, 9-dichloro-3-nitro-pyrido[3,2-b][1,4]benzo[b]thiazines 7. Compounds 4-7 have been characterized by IR, 1H NMR and elemental analysis and screened for antimicrobial activity.
