139221-35-5Relevant academic research and scientific papers
Reactions 1-Acetyl-3-oxo-2,3-dihydroindole with Alkyl 2-Cyano-3-alkoxypropenoate and Alkyl 2-Alkoxycarbonyl-3-alkoxypropenoate. Synthesis of 9-Acetoxypyrroloindol-3-one Derivatives
Merour, J.Y.,Piroelle, S.
, p. 1869 - 1873 (2007/10/02)
1-Acetyl-3-oxo-2,3-dihydroindole reacted with methyl 2-cyano-3-methoxypropenoate and ethyl 2-cyano-3-ethoxypropenoate in the presence of sodium hydride, affording compounds 3 (2-(2-cyano-2-alkoxycarbonylvinyl)-3-hydroxyindole).Methyl 2-methoxycarbonyl-3-methoxypropenoate gave compounds 4 or compounds 5 (in presence of Triton B).Heating compounds 3 or their acetylated derivatives in acetic anhydride at reflux afforded 9-acetoxy-(3H)pyrroloindol-3-one 8.
