1392239-32-5

Basic information

• Product Name: C₁₀H₈BrClO
• Synonyms: C₁₀H₈BrClO
• CAS NO: 1392239-32-5
• Molecular Weight: 259.53
• Mol File: 1392239-32-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₁₀H₈BrClO(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₈BrClO(1392239-32-5)
• EPA Substance Registry System: C₁₀H₈BrClO(1392239-32-5)

Safety Data

• Hazardous Substances Data: 1392239-32-5(Hazardous Substances Data)

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 3160-40-5 4-(4-chlorophenyl)-3-buten-2-one 

Relevant articles and documents

Synthesis of 2-alkenyl-3-hydroxyquinolin-4(1H)-ones as promising antimicrobial and fluorescent agents

2-Alkenyl-3-hydroxyquinolin-4(1H)-ones were prepared by the rearrangement of anthranilic acid esters synthesized by two alternative methods. The prepared derivatives were screened for their antimicrobial activities against representative Gram-positive and

FLAVONE DERIVATIVES AND THEIR PREPARATIVE METHOD AND MEDICAL USE

Flavone derivatives, preparative method of the derivatives and use thereof as medicaments for treating diabetes. The structure of the derivatives is presented by formula 1: In the structure, R1 and R2, which are identical or not, represent hydrogen atom, halogen, cyano, hydroxyl, trifluoromethyl, thio-methyl, benzyloxy, C1-C8 linear chain or branch chain alkyl, C1-C8 linear chain or branch chain alkoxy. The pharmacological test indicates that the flavone derivatives can significantly increase the glucose consumption of Hep-G2 cell with insulin resistance activity, promote translocation of glucose transporter 4 of skeletal muscle cells (L6GLUT4myc) at different level, and significantly increase glucose intake and utilization by cells. The test proves the fact for the first time that the flavone derivatives can significantly promote translocation of glucose transporter 4 of skeletal muscle cells, and one of the mechanisms for treating diabetes is activating the cell AMPK phosphorylation and phosphorylating the downstream ACC.