139225-65-3Relevant academic research and scientific papers
Electrosynthesis of Unsymmetrical Polyaryls by a SRN1-Type Reaction
Boy, P.,Combellas, C.,Suba, C.,Thiebault, A.
, p. 4482 - 4489 (2007/10/02)
Unsymmetrical polyaryls are electrosynthesized in liquid ammonia by a single-step SRN1 reaction in the presence of a redox mediator starting from aromatic halides and 2,6-di-tert-butyl phenoxide.With monoaryl halides activated by electron-withdrawing substituents (N of pyridyl or quinolyl, trifluoromethyl, cyano, sulfone, ester, ketone, alkyl sulfide, N(1+) of anilinium), biaryls are obtained in good yields (between 50 and 95percent).The yields of ter- and quateraryls are lower (40percent maximum).The reaction is extended to other ortho-disubstituted phenols.Elimination reactions of the tert-butyl groups from the products are achieved by a Friedel-Crafts reaction using either trifluoromethanesulfonic acid or aluminum trichloride as catalysts.
Synthesis of Methyl or Aryl Sulfonyl Hydroxy Biphenyls Catalyzed by Monoelectronic Transfer and Related Compounds
Boy, P.,Combellas, C.,Fielding, S.,Thiebault, A.
, p. 6705 - 6708 (2007/10/02)
Methyl or aryl sulfonyl hydroxy biphenyls could be electrosynthesized in liquid ammonia via a SRN1 reaction, from chlorophenyl sulfones and 2,6-ditertbutylphenoxide.Further transformations such as tertbutyl groups elimination, alkylation at the
