1392285-99-2Relevant academic research and scientific papers
Direct synthesis of β-alkyl N-aryl aza Baylis-Hillman adducts via nitroso-ene reaction
Murru, Siva,Gallo, August A.,Srivastava, Radhey S.
experimental part, p. 7119 - 7123 (2012/09/22)
A new approach for the direct Fe-catalyzed synthesis of β-alkyl N-aryl aza Baylis-Hillman (ABH) adducts is reported. This approach involves the formation of a C-N bond via a nitroso-ene reaction. This is a simple, fast, and best alternate method to overcome the substrate scope limitations of the ABH reaction, which converts allyl esters and carbonyl compounds to novel ABH adducts. A variety of arylhydroxylamines reacted with esters, aldehydes, ketone, and nitriles to yield the corresponding products in moderate to excellent yields.
