1392286-47-3

Basic information

• Product Name: 4-(5-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide
• Synonyms: 4-(5-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide
• CAS NO: 1392286-47-3
• Molecular Weight: 465.573
• Mol File: 1392286-47-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(5-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(5-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide(1392286-47-3)
• EPA Substance Registry System: 4-(5-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-2-methyl-3-propionyl-1H-pyrrol-1-yl)benzenesulfonamide(1392286-47-3)

Safety Data

• Hazardous Substances Data: 1392286-47-3(Hazardous Substances Data)

Upstream product

• 3002-24-2 hexane-2,4-dione 
• 76693-04-4 4,4-dimethyl-3,4-dihydro-1H-quinolin-2-one 
• 63-74-1 sulfanilamide 
• 598-21-0 2-Bromoacetyl bromide 

Relevant articles and documents

PYRROLE DERIVATIVES USED AS MODULATORS OF ALPHA7 NACHR

The present invention is related to pyrrole derivatives of formula I as the modulators of nicotinic acetylcholine receptors particularly the α7 subtype. The invention includes pyrrole derivatives, analogues, their prodrugs, their isotopes, their metabolites, pharmaceutically acceptable salts, polymorphs, solvates, optical isomers, clathrates, co-crystals, combinations with suitable medicament and pharmaceutical compositions thereof. The present invention also includes process of preparation of the said compounds and intended use in therapy of them. Owing to the modulatory activity of the pyrrole derivatives on the nicotinic acetylcholine receptors, the invention finds application in the prophylaxis and therapy of disorders encompassing the involvement of cholinergic transmission in the central and peripheral nervous system. The invention relates to the ability of pyrrole derivatives to modulate the cholinergic transmission and efficacy of the endogenous neurotransmitter ACh thorough the nicotinic acetylcholine receptors particularly the α7 subtype.