1392415-03-0Relevant articles and documents
Synthesis of C-4-modified zanamivir analogs as neuraminidase inhibitors and their anti-AIV activities
Ye, Deju,Shin, Woo-Jin,Li, Ning,Tang, Wei,Feng, Enguang,Li, Jian,He, Pei-Lan,Zuo, Jian-Ping,Kim, Hanjo,Nam, Ky-Youb,Zhu, Weiliang,Seong, Baik-Lin,Tai No, Kyoung,Jiang, Hualiang,Liu, Hong
, p. 764 - 770 (2012)
With the introduction of bioisosteres of the guanidinium group together with scaffold hopping, 35 zanamivir analogs with C-4-modification were synthesized, and their inhibitory activities against both group-1 and group-2 neuraminidase (H5N1 and H3N2) were