1392426-75-3

Basic information

• Product Name: 4-[(1,3-benzodioxol-5-ylmethyl)(cyclohexyl)amino]quinazoline-2-carbonitrile
• CAS NO: 1392426-75-3
• Molecular Weight: 386.453
• Mol File: 1392426-75-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[(1,3-benzodioxol-5-ylmethyl)(cyclohexyl)amino]quinazoline-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(1,3-benzodioxol-5-ylmethyl)(cyclohexyl)amino]quinazoline-2-carbonitrile(1392426-75-3)
• EPA Substance Registry System: 4-[(1,3-benzodioxol-5-ylmethyl)(cyclohexyl)amino]quinazoline-2-carbonitrile(1392426-75-3)

Safety Data

• Hazardous Substances Data: 1392426-75-3(Hazardous Substances Data)

Upstream product

• 108-94-1 cyclohexanone 
• 86-96-4 1,2,3,4-tetrahydro-quinazoline-2,4-dione 
• 2620-50-0 1,3-benzodioxol-5-ylmethyl amine 
• 607-68-1 2,4-dichloroquinazoline 
• 227017-79-0 N-(1,3-benzodioxol-5-ylmethyl)cyclohexanamine 

Relevant articles and documents

Tuning and predicting biological affinity: Aryl nitriles as cysteine protease inhibitors

A series of aryl nitrile-based ligands were prepared to investigate the effect of their electrophilicity on the affinity against the cysteine proteases rhodesain and human cathepsin L. Density functional theory calculations provided relative reactivities of the nitriles, enabling prediction of their biological affinity and cytotoxicity and a clear structure-activity relationship.