139244-52-3Relevant academic research and scientific papers
Biosynthesis of Natural Products with a P-C Bond, IX. - Synthesis and Incorporation of (S)- and (R)-2-Hydroxy-ethylphosphonic Acid into Fosfomycin by Streptomyces fradiae
Hammerschmidt, Friedrich
, p. 553 - 558 (2007/10/02)
(S)- and (R)-2-(Benzyloxy)-ethanol (8) were transformed into (S)- and (R)-2-hydroxy-ethylphosphonic acid (13).These were fed to cultures of Streptomyces fradiae.The fosfomycin produced was isolated as aminopropylphosphonic acid and conta
