1392492-59-9

Basic information

• Product Name: 4-chloro-7-(5'-deoxy-α-D-xylofuranosyl)-5-iodo-pyrrolo[2,3-d]pyrimidine
• Synonyms: 4-chloro-7-(5'-deoxy-α-D-xylofuranosyl)-5-iodo-pyrrolo[2,3-d]pyrimidine
• CAS NO: 1392492-59-9
• Molecular Weight: 541.73
• Mol File: 1392492-59-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-chloro-7-(5'-deoxy-α-D-xylofuranosyl)-5-iodo-pyrrolo[2,3-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-7-(5'-deoxy-α-D-xylofuranosyl)-5-iodo-pyrrolo[2,3-d]pyrimidine(1392492-59-9)
• EPA Substance Registry System: 4-chloro-7-(5'-deoxy-α-D-xylofuranosyl)-5-iodo-pyrrolo[2,3-d]pyrimidine(1392492-59-9)

Safety Data

• Hazardous Substances Data: 1392492-59-9(Hazardous Substances Data)

Upstream product

• 3680-69-1 4-chloro-1H-pyrrolo[2,3-d]pyrimidine 
• 1392492-56-6 5-deoxy-3-O-benzoyl-1,2-di(O-acetyl)-D-xylofuranose 
• 123148-78-7 4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine 

Relevant articles and documents

First total synthesis of a naturally occurring iodinated 5′-deoxyxylofuranosyl marine nucleoside

4-Amino-7-(5′-deoxy-β-D-xylofuranosyl)-5-iodo-pyrrolo[2,3-d] pyrimidine 1, an unusual naturally occurring marine nucleoside isolated from an ascidan, Diplosoma sp., was synthesized from D-xylose in seven steps with 28% overall yield on 10 g scale. The key step was Vorbrueggen glycosylation of 5-iodo-pyrrolo[2,3-d]pyrimidine with 5-deoxy-1, 2-O-diacetyl-3-O-benzoyl-D- xylofuranose. Its absolute configuration was confirmed.