139258-97-2Relevant academic research and scientific papers
Study of the anti(myco)bacterial and antitumor activities of prolinate and N-amidocarbothiolprolinate derivatives based on fused tetrahydropyrrolo[3,4-c]pyrrole-1,3(2H,3aH)-dione, bearing an indole ring
Poyraz, Samet,Canacankatan, Necmiye,Belveren, Samet,Yetkin, Derya,Kibar, Kezban,ülger, Mahmut,Sansano, José M.,?zcelik, Nefise Dilek,Necat Y?lmaz,D?nda?, H. Ali
, p. 2253 - 2263 (2018)
Abstract: A series of prolinate and N-amidocarbothiolprolinate derivatives based on a fused pyrrole-3,4-dione core, bearing indole ring systems, are prepared from the corresponding amino acid and an aldehyde via thermal 1,3-dipolar cycloaddition of azomet
Asymmetric synthesis of highly functionalized tetracyclic indole bases embodying the basic skeleton of yohimbine-and reserpine type alkaloids
Lock, Ralf,Waldmann, Herbert
, p. 2753 - 2756 (1996)
Schiff bases derived from tryptophan methyl ester react with differently substituted electron-rich siloxy dienes in the presence of achiral or chiral boric acid esters to give enaminones 5 and 6 with high diastereomer ratios (up to >98:2). These intermedi
Asymmetric Synthesis of Indoloquinolizidin-2-ones Congeners to Yohimbine-Type Alkaloids
Waldmann, Herbert,Braun, Matthias,Weymann, Markus,Gewehr, Markus
, p. 397 - 416 (2007/10/02)
Schiff bases derived from tryptophan methyl ester and tryptamine react with Danishefkys diene in the presence of ZnCl2 to give enaminones which are subsequently transformed into indoloquinolizidin-2-ones by acid-catalyzed cyclization.These tetracyc
N-SUBSTITUTED AMINO ACID DERIVATIVES WITH HYPERALPHALIPOPROTEINAEMIC ACTIVITY
Baggaley, Keith H.,Fears, Robin,Ferres, Harry,Geen, Graham R.,Hatton, Ian K.,et al.
, p. 523 - 532 (2007/10/02)
A series of N-substituted amino acid derivatives was synthesized and the compounds were evaluated for their effects on serum total cholesterol, HDL cholesterol and triglycerides in experimental animals.Hyperalphalipoproteinaemic activity was found for some of these compounds tested, especially BRL 26314 (2) and related 3-aryl-2-aminopropionic acids.Structure-activity relationships are discussed.Keywords: N-substituted amino acid derivatives / hyperalphalipoproteinaemic activity
