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139272-68-7

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139272-68-7 Usage

General Description

Aceclofenac tert-butyl ester is a chemical compound that is derived from the nonsteroidal anti-inflammatory drug (NSAID) aceclofenac. It is an esterified form of aceclofenac, with a tert-butyl group attached to the ester moiety. This modification is believed to enhance the compound's solubility and stability, making it more suitable for pharmaceutical use. Aceclofenac tert-butyl ester retains the anti-inflammatory and analgesic properties of aceclofenac, and it is often used in the treatment of pain and inflammation associated with conditions such as osteoarthritis and rheumatoid arthritis. Studies have shown that this compound exhibits potent anti-inflammatory effects and has potential as a therapeutic agent for the management of inflammatory diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 139272-68-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,9,2,7 and 2 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 139272-68:
(8*1)+(7*3)+(6*9)+(5*2)+(4*7)+(3*2)+(2*6)+(1*8)=147
147 % 10 = 7
So 139272-68-7 is a valid CAS Registry Number.

139272-68-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(tert-butoxy)-2-oxoethyl 2-(2-((2,6-dichlorophenyl)amino)phenyl)acetate

1.2 Other means of identification

Product number -
Other names Aceclofenac Tert-Butyl Ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:139272-68-7 SDS

139272-68-7Downstream Products

139272-68-7Relevant articles and documents

Method for industrially producing aceclofenac

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Paragraph 0029-0030, (2020/11/12)

The invention relates to a method for industrially producing aceclofenac. The method comprises the following steps: mixing organic acid, a water removal agent and Lewis acid, fully stirring, and adding aceclofenac tert-butyl ester for acidolysis reaction. The method is mild in reaction condition, high in reaction rate, free of high temperature and high energy consumption, easy and convenient to operate, environmentally friendly, economical and free of participation or generation of major pollutants, most solvents can be recycled, emission of waste solvents is reduced, and therefore the cost isreduced, and the environment is protected.

Method for producing aceclofenac tert-butyl ester

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Paragraph 0021; 0022, (2019/10/17)

The invention relates to a method for producing aceclofenac tert-butyl ester. The method includes: allowing diclofenac sodium, tert-butyl bromoacetate, catalyst iodide and tetrabutylammonium hydrogensulfate to have reaction in water, slowly cooling, cryst

Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use related applications

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Page/Page column 53, (2010/11/30)

The invention describes novel nitrosated nonsteroidal antiinflammatory drugs (NSAIDs) and pharmaceutically acceptable salts thereof, and novel compositions comprising at least one nitrosated NSAID, and, optionally, at least one compound that donates, transfers or releases nitric oxide, stimulates endogenous synthesis of nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor or is a substrate for nitric oxide synthase, and/or at least one therapeutic agent. The invention also provides novel compositions comprising at least one nitrosated NSAID, and at least one compound that donates, transfers or releases nitric oxide, elevates endogenous levels of endothelium-derived relaxing factor, stimulates endogenous synthesis of nitric oxide or is a substrate for nitric oxide synthase and/or at least one therapeutic agent. The invention also provides novel kits comprising at least one nitrosated NSAID, and, optionally, at least one nitric oxide donor and/or at least one therapeutic agent. The invention also provides methods for treating inflammation, pain and fever; for treating gastrointestinal disorders; for facilitating wound healing; for treating and/or preventing gastrointestinal, renal and/or respiratory toxicities resulting from the use of nonsteroidal antiinflammatory compounds; for treating inflammatory disease states and/or disorders; and for treating and/or preventing ophthalmic diseases and/or disorders.

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