1392779-27-9Relevant articles and documents
Aminocatalytic enantioselective 1,6a additions of alkyl thiols to cyclic dienones: Vinylogous iminiuma ion activation
Tian, Xu,Liu, Yankai,Melchiorre, Paolo
supporting information; experimental part, p. 6439 - 6442 (2012/08/07)
Remote transmission: In the presence of chiral amines, 2,4-dienones are activated toward the attack of a nucleophile at the a position, a mode of activation that is termed vinylogous iminiuma ion catalysis. Specifically, the 1,6a addition of alkyl thiols to β-substituted cyclic dienones was catalyzed by a cinchona-based primary amine; the reaction was highly stereoselective and displayed high selectivity for reaction at the a position. Copyright
